Bring Vaccines to Market Faster

Trusted Vaccine Industry Partner for Over 20 Years

BioProcess International at Biotech Week
September 23-26, 2024
Boston, MA

Visit us at booth 1036!

Wednesday, September 25th at 12:30 pm ET

VaxArray Multiplexed Analytics for mRNA-based Vaccines and Therapeutics

Dr. Erica Dawson
Chief Research and Development Officer
InDevR, Inc.

With the exciting advancement of new technologies such as RNA-based vaccines and therapeutics also comes challenges. Bottlenecks in analytical method development, particularly for multivalent vaccines and drugs, may limit the speed and agility with which new vaccines and therapeutics can be developed and released. This presentation will provide a technology overview and highlight applications of the VaxArray Platform, a multiplexed, microarray-based analytics platform engineered to address a variety of vaccine and therapeutic-relevant applications in protein quantification, mRNA construct quantification and characterization, and serum antibody quantification in a single instrument platform. The VaxArray Platform is comprised of a small-footprint benchtop fluorescence imaging instrument, associated GMP-compatible software, and a variety of off-the-shelf high throughput reagent kits. With multiplexed measurements, VaxArray delivers a range of analytical results and assesses multiple analytes simultaneously with rapid times to result of less than 2 hours and very simple workflow and execution. We will highlight VaxArray applications that include measurements of mRNA construct identity and quantity in multivalent vaccines, quantification of intact and capped mRNA, measurement of multivalent vaccine antigens in traditional vaccines as well as in vitro expressed antigens post-transfection of mRNA constructs, and serum antibody quantification. For projects that fall outside of applications supported by off-the-shelf kits, we will discuss how the Expert Services team at InDevR can rapidly provide validated custom microarrays functionalized with a variety of different biomolecules.

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Simplify 5′ Capping Measurements

Current vaccine manufacturers measure 5′ capping efficiency using complex chromatographic methods that can take 1-2 days with additional queue and analysis time. Reduce analytical turnaround times during mRNA vaccine development and measure 5′ capping efficiency in your laboratory with the 5’CapQ Assay.

  • Get Results Faster – Simplify testing with technology providing highly reproducible results in less than two hours.
  • Analysis at Your Benchtop – Reduce testing bottlenecks by bringing mRNA analytics to your facility.
  • Less Expertise Required – Standardize characterization of your mRNA vaccines on an easy-to-use microarray-based platform.

Maximize Efficiency in Vaccine Development with VaxArray

Discover the VaxArray Platform, your solution in multiplexed immunoassays designed to streamline vaccine development and analysis. This state-of-the-art system offers unparalleled precision and efficiency, empowering researchers to achieve faster, more reliable results in their efforts to advance public health.

  • Multiplex 50+ Analytes in Triplicate – VaxArray multiplexed technology outpaces traditional single-plex methods like ELISA in speed and efficiency.
  • Results in 1 Hour – Faster time to result compared to other technologies.
  • Versatile Platform – analyze a wide range of vaccine-relevant samples, from antibodies and antigens to nucleic acids.

Custom VaxArray for mRNA

Partner with InDevR for comprehensive mRNA customized solutions to simplify mRNA vaccine analytics and accelerate your path to market. InDevR’s Expert Services Team will create custom multiplexed assays to measure mRNA Critical Quality Attributes (CQA) in one platform.